Gene: AT2G25430

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G25430
  • Transcript Identifier AT2G25430.1
  • Gene Type Coding gene
  • Location Chr2 : 10822716-10824677 : positive

Gene Family Information

  • ID HOM05D000291
  • #Genes/#Species 1525/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G25430.1
  • uniprot Q8LF20

Descriptions

  • Description epsin N-terminal homology (ENTH) domain-containing protein / clathrin assembly protein-like protein
  • Computational description epsin N-terminal homology (ENTH) domain-containing protein / clathrin assembly protein-related; FUNCTIONS IN: phospholipid binding, clathrin binding, binding, phosphatidylinositol binding; INVOLVED IN: clathrin coat assembly; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Epsin-like, N-terminal (InterPro:IPR013809), Clathrin adaptor, phosphoinositide-binding, GAT-like (InterPro:IPR014712), ANTH (InterPro:IPR011417), ENTH/VHS (InterPro:IPR008942); BEST Arabidopsis thaliana protein match is: ENTH/ANTH/VHS superfamily protein (TAIR:AT4G32285.2); Has 1786 Blast hits to 1328 proteins in 221 species: Archae - 4; Bacteria - 135; Metazoa - 673; Fungi - 126; Plants - 678; Viruses - 2; Other Eukaryotes - 168 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048268
IEA
Gene Ontologyclathrin coat assembly
GO:0048268
IEA
InterProclathrin coat assembly
GO:0006897
IEA
GOA Databaseendocytosis
GO:0006900
IBA
Gene Ontologyvesicle budding from membrane1
GO:0072583
IBA
Gene Ontologyclathrin-dependent endocytosis1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030276
IEA
GOA Databaseclathrin binding
GO:0030276
IEA
InterProclathrin binding
GO:0005545
IEA
GOA Database1-phosphatidylinositol binding
GO:0005545
IBA
Gene Ontology1-phosphatidylinositol binding1
GO:0005545
IEA
InterPro1-phosphatidylinositol binding
GO:0005543
IEA
GOA Databasephospholipid binding
GO:0005543
IEA
InterProphospholipid binding
GO:0032050
IBA
Gene Ontologyclathrin heavy chain binding1
GO:0000149
IBA
Gene OntologySNARE binding1
GO:0005546
IBA
Gene Ontologyphosphatidylinositol-4,5-bisphosphate binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0030136
IEA
GOA Databaseclathrin-coated vesicle
GO:0030136
IBA
Gene Ontologyclathrin-coated vesicle1
GO:0030136
IEA
InterProclathrin-coated vesicle
GO:0016020
IEA
GOA Databasemembrane
GO:0031410
IEA
GOA Databasecytoplasmic vesicle
GO:0005634
IDA
GOA Databasenucleus
GO:0005905
IEA
GOA Databaseclathrin-coated pit
GO:0005905
IBA
Gene Ontologyclathrin-coated pit1
GO:0005794
IEA
GOA DatabaseGolgi apparatus
GO:0005773
HDA
Gene Ontologyvacuole2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR011417 AP180 N-terminal homology (ANTH) domain
IPR014712 ANTH domain superfamily
IPR008942 ENTH/VHS
IPR013809 ENTH domain
Mapman id Description
22.3.1.7.6 Vesicle trafficking.post-Golgi trafficking.clathrin coated vesicle (CCV) machinery.TPLATE cargo co-adaptor complex.component CAP1/ECA4