Gene: AT2G22780

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G22780
  • Transcript Identifier AT2G22780.1
  • Gene Type Coding gene
  • Location Chr2 : 9689995-9691923 : negative

Gene Family Information

  • ID HOM05D000878
  • #Genes/#Species 677/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G22780.1
  • symbol PMDH1
  • uniprot O82399

Descriptions

  • Description peroxisomal NAD-malate dehydrogenase 1
  • Computational description peroxisomal NAD-malate dehydrogenase 1 (PMDH1); FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of fatty acid beta-oxidation, regulation of photorespiration; LOCATED IN: chloroplast, peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), NAD(P)-binding domain (InterPro:IPR016040), Malate dehydrogenase, NAD-dependent, eukaryote/gamma proteobacteria (InterPro:IPR010097), L-lactate/malate dehydrogenase (InterPro:IPR001557), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: peroxisomal NAD-malate dehydrogenase 2 (TAIR:AT5G09660.1); Has 16991 Blast hits to 16989 proteins in 5457 species: Archae - 237; Bacteria - 11827; Metazoa - 1259; Fungi - 489; Plants - 758; Viruses - 0; Other Eukaryotes - 2421 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006097
IEA
GOA Databaseglyoxylate cycle
GO:0005975
IEA
GOA Databasecarbohydrate metabolic process
GO:0005975
IEA
InterProcarbohydrate metabolic process
GO:0006099
IEA
GOA Databasetricarboxylic acid cycle
GO:0006099
IEA
InterProtricarboxylic acid cycle
GO:0019752
IEA
GOA Databasecarboxylic acid metabolic process
GO:0019752
IEA
InterProcarboxylic acid metabolic process
GO:0080093
IMP
Gene Ontologyregulation of photorespiration1
GO:0031998
IMP, IGI
Gene Ontologyregulation of fatty acid beta-oxidation2
GO:0006108
IEA
Gene Ontologymalate metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0030060
IEA
GOA DatabaseL-malate dehydrogenase activity
GO:0030060
IBA
Gene OntologyL-malate dehydrogenase activity3
GO:0030060
IEA
InterProL-malate dehydrogenase activity
GO:0016616
IEA
GOA Databaseoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016616
IEA
InterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016615
IEA
GOA Databasemalate dehydrogenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISM, IBA
Gene Ontologycytoplasm3
GO:0009507
IDA
GOA Databasechloroplast
GO:0009507
HDA
IBA
Gene Ontologychloroplast3 4
GO:0005777
IEA
GOA Databaseperoxisome
GO:0005777
IDA, HDA
Gene Ontologyperoxisome5 6

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036291 NAD(P)-binding domain superfamily
IPR001557 L-lactate/malate dehydrogenase
IPR022383 Lactate/malate dehydrogenase, C-terminal
IPR010097 Malate dehydrogenase, type 1
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR001236 Lactate/malate dehydrogenase, N-terminal
Mapman id Description
5.7.3.6.5 Lipid metabolism.lipid degradation.fatty acid degradation.glyoxylate cycle.peroxisomal NAD-dependent malate dehydrogenase