Gene: AT1G50430
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G50430
- Transcript Identifier AT1G50430.1
- Gene Type Coding gene
- Location Chr1 : 18682175-18685555 : negative
Gene Family Information
- ID HOM05D001810
- #Genes/#Species 362/100
- Phylogenetic origin
- ID ORTHO05D005662
- #Genes/#Species 154/98
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G50430.1
- symbol DWF5
- Alias 7RED,DELTA5,7-STEROL DELTA7 REDUCTASE,LE,LEPIDA,PA,PARVA,ST7R,STEROL DELTA7 REDUCTASE
- full_name DWARF 5
- uniprot Q9LDU6
Descriptions
- Description Ergosterol biosynthesis ERG4/ERG24 family
- Computational description DWARF 5 (DWF5); FUNCTIONS IN: sterol delta7 reductase activity; INVOLVED IN: sterol biosynthetic process, unidimensional cell growth, brassinosteroid biosynthetic process; LOCATED IN: integral to endoplasmic reticulum membrane, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Sterol reductase, conserved site (InterPro:IPR018083), Ergosterol biosynthesis ERG4/ERG24 (InterPro:IPR001171); BEST Arabidopsis thaliana protein match is: Ergosterol biosynthesis ERG4/ERG24 family (TAIR:AT3G52940.1); Has 989 Blast hits to 986 proteins in 209 species: Archae - 0; Bacteria - 51; Metazoa - 267; Fungi - 416; Plants - 150; Viruses - 3; Other Eukaryotes - 102 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006694 | IEA | GOA Database | steroid biosynthetic process | |
| GO:0016126 | IEA | GOA Database | sterol biosynthetic process | |
| GO:0016126 | IBA TAS | Gene Ontology | sterol biosynthetic process | 1 2 |
| GO:0016126 | IEA | InterPro | sterol biosynthetic process | |
| GO:0008203 | IEA | GOA Database | cholesterol metabolic process | |
| GO:0008202 | IEA | GOA Database | steroid metabolic process | |
| GO:0006695 | IEA | GOA Database | cholesterol biosynthetic process | |
| GO:0006629 | IEA | GOA Database | lipid metabolic process | |
| GO:0016132 | IMP IBA | Gene Ontology | brassinosteroid biosynthetic process | 1 2 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016628 | IEA | Gene Ontology | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | |
| GO:0016628 | IEA | InterPro | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | |
| GO:0016491 | IEA | GOA Database | oxidoreductase activity | |
| GO:0009918 | IMP IBA | Gene Ontology | sterol delta7 reductase activity | 1 2 |
| GO:0016627 | IBA | Gene Ontology | oxidoreductase activity, acting on the CH-CH group of donors | 2 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 3 |
| GO:0047598 | IEA | Gene Ontology | 7-dehydrocholesterol reductase activity |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0016020 | IEA | InterPro | membrane | |
| GO:0005783 | IEA | GOA Database | endoplasmic reticulum | |
| GO:0016021 | IEA | GOA Database | integral component of membrane | |
| GO:0005886 | IDA | GOA Database | plasma membrane | |
| GO:0005794 | IDA | GOA Database | Golgi apparatus | |
| GO:0005794 | HDA | Gene Ontology | Golgi apparatus | 4 |
| GO:0005789 | IEA | GOA Database | endoplasmic reticulum membrane | |
| GO:0005634 | HDA ISM | Gene Ontology | nucleus | 5 |
| GO:0030176 | IDA IBA | Gene Ontology | integral component of endoplasmic reticulum membrane | 2 6 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR001171 | Ergosterol biosynthesis ERG4/ERG24 |
| Mapman id | Description |
|---|---|
| 5.5.1.6 | Lipid metabolism.phytosterol biosynthesis.plant sterol pathway.sterol delta7 reductase |