Gene: AT1G16970

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G16970
  • Transcript Identifier AT1G16970.1
  • Gene Type Coding gene
  • Location Chr1 : 5801159-5805724 : negative

Gene Family Information

  • ID HOM05D006139
  • #Genes/#Species 129/95
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G16970.1
  • symbol KU70
  • Alias ATKU70,ARABIDOPSIS THALIANA KU70 HOMOLOG
  • full_name KU70 homolog
  • uniprot Q9FQ08

Descriptions

  • Description ATP-dependent DNA helicase 2 subunit Ku70-like protein
  • Computational description KU70 homolog (KU70); FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: DNA repair, response to heat, telomere maintenance; LOCATED IN: nucleus, DNA-dependent protein kinase-DNA ligase 4 complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA-binding SAP (InterPro:IPR003034), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), DNA helicase, ATP-dependent, Ku70 subunit (InterPro:IPR006165); Has 475 Blast hits to 466 proteins in 181 species: Archae - 0; Bacteria - 6; Metazoa - 182; Fungi - 177; Plants - 52; Viruses - 0; Other Eukaryotes - 58 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006303
IEA
GOA Databasedouble-strand break repair via nonhomologous end joining
GO:0006303
IMP
IBA
Gene Ontologydouble-strand break repair via nonhomologous end joining1 2
GO:0006303
IEA
InterProdouble-strand break repair via nonhomologous end joining
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
TAS
Gene OntologyDNA repair3
GO:0000723
IEA
GOA Databasetelomere maintenance
GO:0000723
IDA
IBA
TAS
Gene Ontologytelomere maintenance1 3 4
GO:0000723
IEA
InterProtelomere maintenance
GO:0071480
IBA
Gene Ontologycellular response to gamma radiation1
GO:0009408
IEP
Gene Ontologyresponse to heat5
GO:0071481
IBA
Gene Ontologycellular response to X-ray1
GO:0032508
IEA
GOA DatabaseDNA duplex unwinding

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0004386
IEA
GOA Databasehelicase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0042162
IEA
GOA Databasetelomeric DNA binding
GO:0042162
IBA
Gene Ontologytelomeric DNA binding1
GO:0042162
IEA
InterProtelomeric DNA binding
GO:0003684
IEA
Gene Ontologydamaged DNA binding
GO:0003684
IEA
InterProdamaged DNA binding
GO:0003678
IEA
Gene OntologyDNA helicase activity
GO:0003678
IEA
InterProDNA helicase activity
GO:0005515
IPI
Gene Ontologyprotein binding6
GO:0003690
IDA
Gene Ontologydouble-stranded DNA binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043564
IEA
GOA DatabaseKu70:Ku80 complex
GO:0043564
IBA
Gene OntologyKu70:Ku80 complex1
GO:0043564
IEA
InterProKu70:Ku80 complex
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0005634
IEA
InterPronucleus
GO:0005737
IEA
GOA Databasecytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR016194 SPOC-like, C-terminal domain superfamily
IPR006165 Ku70
IPR036465 von Willebrand factor A-like domain superfamily
IPR005160 Ku70/Ku80 C-terminal arm
IPR005161 Ku70/Ku80, N-terminal alpha/beta
IPR036361 SAP domain superfamily
IPR006164 Ku70/Ku80 beta-barrel domain
IPR027388 Ku70, bridge and pillars domain superfamily
IPR003034 SAP domain
Mapman id Description
14.4.1.1 DNA damage response.nonhomologous end-joining (NHEJ) repair.Ku70-Ku80 helicase complex.component KU70