Gene: AT1G10930
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G10930
- Transcript Identifier AT1G10930.1
- Gene Type Coding gene
- Location Chr1 : 3648032-3654997 : negative
Gene Family Information
- ID HOM05D000246
- #Genes/#Species 1713/100
- Phylogenetic origin
- ID ORTHO05D005396
- #Genes/#Species 158/98
- Phylogenetic origin
Gene Duplication Information
- Tandem Duplication Tandem duplicate
Labels
Identifiers
- tid AT1G10930.1
- symbol RECQ4A
- uniprot Q8L840
Descriptions
- Description DNA helicase (RECQl4A)
- Computational description RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink).
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Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006281 | IMP IBA | Gene Ontology | DNA repair | 1 2 |
| GO:0006281 | IEA | InterPro | DNA repair | |
| GO:0006310 | IEA | GOA Database | DNA recombination | |
| GO:0006310 | IMP IBA | Gene Ontology | DNA recombination | 1 2 |
| GO:0006310 | IEA | InterPro | DNA recombination | |
| GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus | |
| GO:0006974 | IMP, IGI | Gene Ontology | cellular response to DNA damage stimulus | 1 |
| GO:0044237 | IEA | GOA Database | cellular metabolic process | |
| GO:0044237 | IEA | InterPro | cellular metabolic process | |
| GO:0006260 | IEA | GOA Database | DNA replication | |
| GO:0006260 | IEA | InterPro | DNA replication | |
| GO:0016070 | ISO | PLAZA Integrative Orthology | RNA metabolic process | Solyc01g103960.3 |
| GO:0051276 | IMP | Gene Ontology | chromosome organization | 3 |
| GO:0070417 | IEP | Gene Ontology | cellular response to cold | 4 |
| GO:0071215 | IEP | Gene Ontology | cellular response to abscisic acid stimulus | 4 |
| GO:0000723 | IMP | Gene Ontology | telomere maintenance | 1 |
| GO:0000724 | IMP, IGI IBA | Gene Ontology | double-strand break repair via homologous recombination | 1 2 |
| GO:0006268 | IBA | Gene Ontology | DNA unwinding involved in DNA replication | 2 |
| GO:0032508 | IBA | Gene Ontology | DNA duplex unwinding | 2 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0043138 | IEA | GOA Database | 3'-5' DNA helicase activity | |
| GO:0043138 | IDA, IMP IBA | Gene Ontology | 3'-5' DNA helicase activity | 1 2 3 |
| GO:0043138 | IEA | InterPro | 3'-5' DNA helicase activity | |
| GO:0003678 | IEA | GOA Database | DNA helicase activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0000166 | IEA | InterPro | nucleotide binding | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0004386 | IEA | GOA Database | helicase activity | |
| GO:0004386 | IEA | InterPro | helicase activity | |
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0005524 | IEA | InterPro | ATP binding | |
| GO:0003676 | IEA | Gene Ontology | nucleic acid binding | |
| GO:0003676 | IEA | InterPro | nucleic acid binding | |
| GO:0003724 | ISO | PLAZA Integrative Orthology | RNA helicase activity | Solyc01g103960.3 |
| GO:0009378 | IBA | Gene Ontology | four-way junction helicase activity | 2 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | ISM, IBA | Gene Ontology | nucleus | 2 |
| GO:0009506 | IDA | GOA Database | plasmodesma | |
| GO:0009506 | HDA | Gene Ontology | plasmodesma | 5 |
| GO:0005694 | IEA | GOA Database | chromosome | |
| GO:0005694 | IBA | Gene Ontology | chromosome | 2 |
| GO:0005737 | IBA | Gene Ontology | cytoplasm | 2 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR010997 | HRDC-like superfamily |
| IPR011545 | DEAD/DEAH box helicase domain |
| IPR018982 | RQC domain |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR044876 | HRDC domain superfamily |
| IPR002121 | HRDC domain |
| IPR032284 | ATP-dependent DNA helicase RecQ, zinc-binding domain |
| IPR004589 | DNA helicase, ATP-dependent, RecQ type |
| IPR001650 | Helicase, C-terminal |
| IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Mapman id | Description |
|---|---|
| 13.3.5.5.3.1 | Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic crossover.RTR Holliday junction dissolution complex.helicase component RecQ4A |