Gene: AT1G01880

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G01880
  • Transcript Identifier AT1G01880.3
  • Gene Type Coding gene
  • Location Chr1 : 306558-308991 : negative

Gene Family Information

  • ID HOM05D006373
  • #Genes/#Species 125/96
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G01880.3
  • Alias AtGEN1,GEN1,ortholog of HsGEN1
  • uniprot Q9LPD2

Descriptions

  • Description 5'-3' exonuclease family protein
  • Computational description 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: single-stranded DNA endonuclease family protein (TAIR:AT3G48900.2); Has 2133 Blast hits to 1941 proteins in 373 species: Archae - 274; Bacteria - 9; Metazoa - 492; Fungi - 719; Plants - 217; Viruses - 17; Other Eukaryotes - 405 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0090305
IEA
GOA Databasenucleic acid phosphodiester bond hydrolysis
GO:0090305
IDA
Gene Ontologynucleic acid phosphodiester bond hydrolysis1
GO:0009555
IBA
Gene Ontologypollen development2
GO:0009650
IGI
Gene OntologyUV protection3
GO:0006259
IDA
Gene OntologyDNA metabolic process1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003697
ISO
PLAZA Integrative Orthologysingle-stranded DNA binding Os09g0521900
GO:0003690
ISO
PLAZA Integrative Orthologydouble-stranded DNA binding Os09g0521900
GO:0048256
ISO
PLAZA Integrative Orthologyflap endonuclease activity Os09g0521900
GO:0005515
ISO
PLAZA Integrative Orthologyprotein binding Os09g0521900
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0003677
IEA
Gene OntologyDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0004518
IEA
GOA Databasenuclease activity
GO:0004518
IEA
InterPronuclease activity
GO:0004519
IEA
GOA Databaseendonuclease activity
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0017108
IDA
IBA
Gene Ontology5'-flap endonuclease activity1 2
GO:0008821
IDA
Gene Ontologycrossover junction endodeoxyribonuclease activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR006084 XPG/Rad2 endonuclease
IPR029060 PIN-like domain superfamily
IPR006085 XPG, N-terminal
IPR006086 XPG-I domain
IPR008918 Helix-hairpin-helix motif, class 2
IPR036279 5'-3' exonuclease, C-terminal domain superfamily
Mapman id Description
13.3.5.5.2.3 Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic crossover.class II interference-insensitive crossover pathway.Holliday junction resolvase (GEN1)