Module
- Number
- 59
- Regulatory Genes
- 4
- Module Genes
- 27
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
somi-1 | M04G12.4 | WBGene00010868 | 651 | View | |
tir-1 | F13B10.1 | WBGene00006575 | 195 |
tir-1 encodes a protein that may be involved in apoptosis: from N- to C-terminus, it has three domains; the first two are sterile alpha motif (SAM) domains; the last is a Toll-interleukin 1 (IL1) receptor (TIR) domain.
|
View |
T22E7.2 | T22E7.2 | WBGene00020694 | 140 | View | |
tag-233 | D2021.2 | WBGene00044071 | 113 | View |
CLR Predictions
103 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
abts-4 | R03E9.3 | WBGene00019844 |
abts-4 encodes an anion transporter; ABTS-4::GFP fusion proteins are expressed solely in the intestine, with highest levels seen in the most anterior and posterior gut cells and subcellular localization restricted to the basolateral membrane.
|
View |
C01B12.2 | C01B12.2 | WBGene00015285 | View | |
C02B10.3 | C02B10.3 | WBGene00015328 |
C02B10.3 encodes a predicted secreted protein containing EGF-like repeats.
|
View |
C15C7.7 | C15C7.7 | WBGene00015793 | View | |
C17H11.6 | C17H11.6 | WBGene00015926 | View | |
C34F6.10 | C34F6.10 | WBGene00007944 | View | |
C56G2.1 | C56G2.1 | WBGene00016977 | View | |
cgef-1 | C14A11.3 | WBGene00006496 | View | |
daf-19 | F33H1.1 | WBGene00000914 |
daf-19 is the sole C. elegans member of the RFX family of transcription factors, and is required for sensory neuron cilium formation; DAF-19 is expressed in ciliated sensory neurons during the period that their cilia are generated, and probably functions as an common transcriptional activator of many genes that specifically encode cilial structures in sensory neurons; daf-19 mutants lack sensory cilia, have abnormal amphids, are strongly dauer-constutive, lack normal openings of the amphids to the external environment (i.e., fail to show dye-filling), and are highly defective in their ability to taste or smell; DAF-19 regulates bbs-5, che-2, che-13, dyf-3, osm-1, osm-6, and xbx-1 expression, and probably regulates ~200 other genes (e.g., bbs-2, bbs-7 and bbs-8); the localization of DAF-6 is aberrant in daf-19 mutants.
|
View |
dgk-2 | F46H6.2 | WBGene00000959 |
dgk-2 encodes a putative diacylglycerol kinase.
|
View |
dhs-27 | C04F6.5 | WBGene00000990 |
dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial.
|
View |
F21A10.2 | F21A10.2 | WBGene00008999 | View | |
F42G8.5 | F42G8.5 | WBGene00018356 | View | |
F52G3.1 | F52G3.1 | WBGene00018710 | View | |
F57A8.1 | F57A8.1 | WBGene00010177 | View | |
M176.11 | M176.11 | WBGene00010947 | View | |
nhr-4 | F32B6.1 | WBGene00003603 |
nhr-4 is predicted to encode a nuclear hormone receptor (NHR); expression may peak during the late larval stages, based on mRNA expression analysis.
|
View |
pqn-34 | F35B3.5 | WBGene00004121 |
The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
|
View |
puf-9 | W06B11.2 | WBGene00004245 |
The puf-9 gene encodes a predicted RNA binding protein orthologous to Drosophila PUMILIO and human PUMILIO 2 (OMIM:607205); PUF-9 is required for normal locomotion and fluid balance, and is expressed primarily in somatic tissues; PUF-9 contains a glutamine/asparagine-rich domain.
|
View |
rab-6.2 | T25G12.4 | WBGene00004270 |
rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction.
|
View |
rgl-1 | F28B4.2 | WBGene00017891 | View | |
T15H9.1 | T15H9.1 | WBGene00011787 | View | |
T21H8.1 | T21H8.1 | WBGene00011904 |
T21H8.1 encodes the C. elegans ortholog of human beta-liprin, a coiled-coil domain-containing protein that interacts with alpha-liprin, a transmembrane protein-tyrosine phosphatase-interacting protein; as loss of T21H8.1 activity via large-scale RNAi results in no obvious abnormalities, the precise role of T21H8.1 in C. elegans development and/or behavior is not yet known; however, by virtue of its similarity to human beta-liprin, the protein product of T21H8.1 is predicted to function as part of a protein complex that localizes to focal adhesions and regulates cell-extracellular matrix interactions; a T21H8.1 promoter::GFP fusion construct directs expression in pharyngeal and body wall muscles, and in regions adjacent to the dorsal and ventral nerve cords; expression in the pharynx is particularly strong in the posterior bulb.
|
View |
tag-233 | D2021.2 | WBGene00044071 | View | |
tag-250 | C29E4.5 | WBGene00016203 | View | |
Y41D4A.4 | Y41D4A.4 | WBGene00021506 | View | |
ztf-12 | C01B7.1 | WBGene00015274 | View |