Module
- Number
- 5
- Regulatory Genes
- 6
- Module Genes
- 134
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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nhr-276 | Y71A12C.1 | WBGene00013512 | 669 | View | |
srg-7 | C18F10.8 | WBGene00005165 | 487 | View | |
R03E1.4 | R03E1.4 | WBGene00010995 | 431 | View | |
srg-33 | F21F8.1 | WBGene00005190 | 140 | View | |
srg-62 | C24B9.12 | WBGene00005219 | 125 | View | |
nhr-262 | F09C6.8 | WBGene00008619 | 105 | View |
CLR Predictions
7 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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B0462.1 | B0462.1 | WBGene00007181 | View | |
C02H6.1 | C02H6.1 | WBGene00015361 | View | |
C04B4.4 | C04B4.4 | WBGene00007292 | View | |
C04E6.4 | C04E6.4 | WBGene00015421 | View | |
C08E8.2 | C08E8.2 | WBGene00007438 | View | |
C09G1.3 | C09G1.3 | WBGene00007485 | View | |
C11E4.4 | C11E4.4 | WBGene00007519 | View | |
C13A2.6 | C13A2.6 | WBGene00015723 | View | |
C16D9.3 | C16D9.3 | WBGene00015858 | View | |
C18H2.4 | C18H2.4 | WBGene00015991 |
C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
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C46H3.1 | C46H3.1 | WBGene00016724 | View | |
C47F8.6 | C47F8.6 | WBGene00008162 | View | |
C54C6.4 | C54C6.4 | WBGene00008286 | View | |
che-1 | C55B7.12 | WBGene00000483 |
che-1 encodes a C2H2-type zinc finger-containing transcription factor orthologous to Drosophila GLASS, which is required for photoreceptor cell differentiation; CHE-1 is required for determining the identity and function of the amphid ASE neurons, the major neurons that mediate chemotaxis to water-soluble attractants; CHE-1 is expressed predominantly in the ASE neurons and regulates, either directly or indirectly, the expression of a number of ASE-specific genes.
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clec-102 | F33E2.3 | WBGene00009359 | View | |
clec-134 | W10G11.11 | WBGene00021141 | View | |
clec-158 | R13F6.8 | WBGene00020067 | View | |
clec-259 | M162.1 | WBGene00010927 | View | |
clec-38 | T25E12.10 | WBGene00012025 | View | |
E02H9.7 | E02H9.7 | WBGene00017105 | View | |
eat-2 | Y48B6A.4 | WBGene00001133 |
eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
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F10A3.12 | F10A3.12 | WBGene00008637 | View | |
F18G5.5 | F18G5.5 | WBGene00017581 | View | |
F21C10.1 | F21C10.1 | WBGene00017652 | View | |
F21F12.1 | F21F12.1 | WBGene00009022 | View | |
F26C11.3 | F26C11.3 | WBGene00009147 | View | |
F28B1.5 | F28B1.5 | WBGene00009199 | View | |
F34D6.2 | F34D6.2 | WBGene00018022 | View | |
F37E3.2 | F37E3.2 | WBGene00018157 | View | |
F39G3.4 | F39G3.4 | WBGene00018209 | View | |
F40F12.4 | F40F12.4 | WBGene00009593 | View | |
F41D3.9 | F41D3.9 | WBGene00009614 | View | |
F46B3.16 | F46B3.16 | WBGene00009767 | View | |
F56D2.8 | F56D2.8 | WBGene00018968 | View | |
F56H6.3 | F56H6.3 | WBGene00010164 | View | |
F58E1.7 | F58E1.7 | WBGene00019038 | View | |
F59C6.8 | F59C6.8 | WBGene00010327 | View | |
fbxa-220 | Y66A7A.1 | WBGene00013421 | View | |
fbxa-94 | F28F8.8 | WBGene00009225 | View | |
H04M03.11 | H04M03.11 | WBGene00019155 | View | |
K02B9.3 | K02B9.3 | WBGene00010494 | View | |
K02F6.4 | K02F6.4 | WBGene00019338 | View | |
K06G5.3 | K06G5.3 | WBGene00010607 | View | |
K09D9.3 | K09D9.3 | WBGene00019566 | View | |
M01G12.14 | M01G12.14 | WBGene00010825 | View | |
M04C7.3 | M04C7.3 | WBGene00010854 | View | |
nhr-111 | F44G3.9 | WBGene00003701 |
nhr-111 encodes a member of the nuclear receptor superfamily; by homology, NHR-111 is predicted to function as a ligand-dependent transcriptional regulator, but as loss of nhr-111 activity via large-scale RNAi screens does not result in any abnormalities, the precise role of NHR-111 in C. elegans development and/or behavior is not yet known; an nhr-111 reporter construct is expressed in embryos and early larvae in a pair of neurons in the ventral ganglion of the head and in two cells that may be the somatic gonad precursors.
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nhr-240 | Y60A3A.15 | WBGene00013363 | View | |
nhr-253 | ZK6.4 | WBGene00022639 | View | |
R03E1.4 | R03E1.4 | WBGene00010995 | View | |
R06B9.2 | R06B9.2 | WBGene00011053 | View | |
R07C12.3 | R07C12.3 | WBGene00019933 | View | |
ser-1 | F59C12.2 | WBGene00004776 |
ser-1 encodes a putative ortholog of mammalian 5-HT2 metabotropic serotonin receptors; SER-1 is required in both vulval muscle and neurons for the stimulation of egg-laying by serotonin (5-HT), but is completely dispensable for stimulation by the uptake inhibitor fluoxetine, and mostly dispensable for stimulation by the tricyclic antidepressant imipramine; SER-1 and SER-7 are redundantly required for normal egg-laying; SER-1 is required for normal turning during male mating, and ser-1 mutants show reduced male tail curling in exogenous 5-HT, but ser-1 males retain mating ability in the laboratory; SER-1 is weakly required for pharyngeal pumping; SER-1 is expressed in diverse neurons (head, nerve ring, vulval, ventral cord motoneurons, tail, and many others), in diverse muscles (pharyngeal, vulval, and male-specific diagonal), and in uterine cells; stimulation of heterologously expressed SER-1 induces a rise in free intracellular calcium; SER-1 has low affinity for 5-HT, and a mixture of pharmacological similarities to mammalian 5-HT1 and 5-HT2 receptors; SER-1 is stimulated by alpha-methyl-5HT, and probably antagonized by methiotheptin; SER-1 is coexpressed with MPZ-1, has a PDZ binding motif (ETFL) that aids its signalling, and binds PDZ domain 10 of MPZ-1 in vitro; SER-1's stimulation of egg-laying is impeded by mpz-1(RNAi), if and only if SER-1's ETFL motif is intact; mod-1;ser-1 double mutants subtly overbend their bodies while moving backward.
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smp-2 | D1037.2 | WBGene00004890 | View | |
snf-7 | ZK1010.9 | WBGene00004906 | View | |
sra-31 | C56C10.5 | WBGene00005057 | View | |
srab-18 | T11A5.3 | WBGene00011702 | View | |
srbc-17 | C45H4.3 | WBGene00016687 | View | |
srbc-40 | H24O09.1 | WBGene00019242 | View | |
srbc-5 | T28A11.7 | WBGene00020874 | View | |
srbc-73 | Y32B12A.2 | WBGene00012517 | View | |
srd-10 | Y45F10B.14 | WBGene00005088 | View | |
srd-28 | M01B2.2 | WBGene00005106 | View | |
srg-31 | T07H8.5 | WBGene00005188 | View | |
srg-36 | K04C1.6 | WBGene00005193 | View | |
srg-7 | C18F10.8 | WBGene00005165 | View | |
srh-119 | Y102A5C.21 | WBGene00005338 | View | |
srh-15 | C50B6.6 | WBGene00005240 | View | |
srh-150 | K08G2.2 | WBGene00005366 | View | |
srh-171 | Y60A3A.5 | WBGene00005387 | View | |
srh-180 | F57G8.1 | WBGene00005395 | View | |
srh-181 | ZK228.6 | WBGene00005396 | View | |
srh-183 | Y60A3A.3 | WBGene00005398 | View | |
srh-188 | ZK105.7 | WBGene00022658 | View | |
srh-239 | T26H5.3 | WBGene00005446 | View | |
srh-266 | F31F4.6 | WBGene00005472 | View | |
srh-282 | T21D12.5 | WBGene00005487 | View | |
srh-293 | K08G2.8 | WBGene00005497 | View | |
srh-30 | ZC404.12 | WBGene00005253 | View | |
srh-52 | R08H2.7 | WBGene00005275 | View | |
srh-54 | T09F5.6 | WBGene00005277 | View | |
srh-71 | T10D4.5 | WBGene00005292 | View | |
sri-25 | C41G6.10 | WBGene00005537 | View | |
sri-60 | Y47G7B.3 | WBGene00005572 | View | |
sri-62 | F34D6.5 | WBGene00005574 | View | |
sri-71 | D2062.3 | WBGene00005583 | View | |
sri-8 | ZK666.10 | WBGene00005520 | View | |
srj-19 | Y45G12C.14 | WBGene00005607 | View | |
srr-7 | T01G5.4 | WBGene00005658 | View | |
srt-29 | C24B9.5 | WBGene00016050 | View | |
srt-69 | B0238.8 | WBGene00015072 | View | |
sru-21 | C08F11.4 | WBGene00005684 | View | |
sru-24 | F31F4.13 | WBGene00005687 | View | |
srw-47 | K10G4.2 | WBGene00005794 | View | |
srw-84 | Y43F8A.4 | WBGene00005831 | View | |
srx-107 | F40H7.10 | WBGene00005998 | View | |
srx-118 | T21B4.12 | WBGene00006009 | View | |
srx-59 | T07H8.3 | WBGene00005950 | View | |
srx-85 | F38B7.4 | WBGene00005976 | View | |
srxa-3 | W07A8.4 | WBGene00012320 | View | |
srz-18 | F46B3.11 | WBGene00009763 | View | |
srz-56 | C39B5.1 | WBGene00016519 | View | |
srz-7 | T17A3.11 | WBGene00020547 | View | |
str-124 | T22H6.3 | WBGene00006175 | View | |
str-141 | F47G9.2 | WBGene00006189 | View | |
str-204 | F10D2.1 | WBGene00006237 | View | |
str-209 | F26G5.5 | WBGene00006242 | View | |
str-217 | Y102A5C.28 | WBGene00006249 | View | |
str-247 | B0213.9 | WBGene00006274 | View | |
str-255 | C45H4.15 | WBGene00006281 | View | |
str-55 | F26D2.7 | WBGene00006120 | View | |
str-68 | Y73C8C.6 | WBGene00006130 | View | |
str-92 | F59A1.3 | WBGene00006150 | View | |
T04G9.6 | T04G9.6 | WBGene00020217 | View | |
T05A8.2 | T05A8.2 | WBGene00020228 | View | |
T06E4.7 | T06E4.7 | WBGene00011534 | View | |
T09E11.10 | T09E11.10 | WBGene00011659 | View | |
T20B12.5 | T20B12.5 | WBGene00020603 | View | |
T24C12.1 | T24C12.1 | WBGene00020764 | View | |
T25G12.1 | T25G12.1 | WBGene00020809 | View | |
unc-63 | Y110A7A.3 | WBGene00006797 |
unc-63 encodes an alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-63 is required for normal locomotion and regulation of egg-laying behavior, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-29 and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-63 is expressed in body wall muscles, vulval muscles, and a large number of neurons; UNC-63 is a member of the UNC-38-like group of nAChR subunits.
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Y116A8A.4 | Y116A8A.4 | WBGene00013775 | View | |
Y116A8C.5 | Y116A8C.5 | WBGene00013786 |
Y116A8C.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; Y116A8C.5 has no clear orthologs in other organisms.
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Y18D10A.26 | Y18D10A.26 | WBGene00023459 | View | |
Y19D10B.2 | Y19D10B.2 | WBGene00021231 | View | |
Y37H2C.4 | Y37H2C.4 | WBGene00012575 | View | |
Y40B10A.5 | Y40B10A.5 | WBGene00021490 | View | |
Y48G9A.12 | Y48G9A.12 | WBGene00021705 | View | |
Y49F6A.1 | Y49F6A.1 | WBGene00021711 | View | |
Y50D7A.3 | Y50D7A.3 | WBGene00021753 |
Y50D7A.3 is orthologous to human PHOSPHORYLASE KINASE, TESTIS/LIVER, GAMMA-2 (PHKG2; OMIM:172471), which when mutated leads to liver glycogenosis and cirrhosis.
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Y53C10A.3 | Y53C10A.3 | WBGene00013134 |
Y53C10A.3 encodes a paralog of HSF-1 that might regulate ubq-1, since ubq-1 has 5'-flanking sequences resembling heat shock regulatory elements, yet is uninduced by heat shock.
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Y60A9.1 | Y60A9.1 | WBGene00013368 | View | |
Y71A12B.10 | Y71A12B.10 | WBGene00013507 | View | |
ZK550.1 | ZK550.1 | WBGene00013995 | View |