Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

unc-63  

Sequence Name

Y110A7A.3  

WB ID

WBGene00006797  

Description

unc-63 encodes an alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-63 is required for normal locomotion and regulation of egg-laying behavior, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-29 and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-63 is expressed in body wall muscles, vulval muscles, and a large number of neurons; UNC-63 is a member of the UNC-38-like group of nAChR subunits.