Module
- Number
- 28
- Regulatory Genes
- 4
- Module Genes
- 34
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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atf-5 | T04C10.4 | WBGene00000221 | 826 |
atf-5 encodes a homolog of the mammalian bZIP transcription factors ATF4 and ATF5, analogous to GCN4 in S. cerevisiae; like like ATF4 and GCN4, atf-5 has an extensive 5' UTR with one 37-residue uORF; ATF4 is poorly translated in unstressed cells but well-translated during ER stress, amino acid starvation, or arsenite treatment; possibly atf-5 is also translationally regulated in a way similar to ATF4.
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hmg-1.1 | Y48B6A.14 | WBGene00001971 | 296 |
hmg-1.1 encodes a member of the high mobility group (HMG) family of proteins.
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nhr-152 | C12D5.2 | WBGene00015705 | 192 | View | |
Y65B4BR.5 | Y65B4BR.5 | WBGene00022042 | 172 | View |
CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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rack-1 | K04D7.1 | WBGene00010556 | View | |
rla-1 | Y37E3.7 | WBGene00004409 |
rla-1 encodes an acidic ribosomal subunit protein P1.
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rpa-0 | F25H2.10 | WBGene00004408 |
rpa-0 encodes an acidic ribosomal subunit protein P0.
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rpl-13 | C32E8.2 | WBGene00004425 |
rpl-13 encodes a large ribosomal subunit L13 protein.
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rpl-15 | K11H12.2 | WBGene00004427 |
rpl-15 encodes a large ribosomal subunit L15 protein.
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rpl-20 | E04A4.8 | WBGene00004432 |
rpl-20 encodes a large ribosomal subunit L18a protein.
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rpl-22 | C27A2.2 | WBGene00004434 |
rpl-22 encodes a large ribosomal subunit L22 protein; by homology, RPL-22 is predicted to function in protein biosynthesis; in C. elegans, RPL-22 activity is broadly required for embryonic and germline development, as well as normal body coloration, morphology, and postembryonic growth rates.
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rpl-24.1 | D1007.12 | WBGene00004436 |
rpl-24.1 encodes a large ribosomal subunit L24 protein.
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rpl-27 | C53H9.1 | WBGene00004441 |
rpl-27 encodes a large ribosomal subunit L27 protein.
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rpl-3 | F13B10.2 | WBGene00004414 |
rpl-3 encodes a large ribosomal subunit L3 protein required in mass RNAi assays for embryonic and larval viability, fertility, and general health; the rpl-3 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-3 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-7, rpl-10, rpl-12) have protein products that are involved in translation.
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rpl-30 | Y106G6H.3 | WBGene00004444 |
rpl-30 encodes a large ribosomal subunit L30 protein; by homology, RPL-30 is predicted to function in protein biosynthesis; in C. elegans, loss of rpl-30 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
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rpl-31 | W09C5.6 | WBGene00004445 |
rpl-31 encodes a large ribosomal subunit L31 protein.
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rpl-32 | T24B8.1 | WBGene00004446 |
rpl-32 encodes a large ribosomal subunit L32 protein.
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rpl-35 | ZK652.4 | WBGene00004449 |
rpl-35 encodes a large ribosomal subunit L35 protein.
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rpl-36 | F37C12.4 | WBGene00004450 |
rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates.
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rpl-4 | B0041.4 | WBGene00004415 |
rpl-4 encodes a large ribosomal subunit L4 protein.
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rpl-5 | F54C9.5 | WBGene00004416 |
rpl-5 encodes a large ribosomal subunit L5 protein; by homology, RPL-5 is predicted to function in protein biosynthesis; in C. elegans RPL-5 activity is broadly required for embryonic, larval, germline, and vulval development, as well as normal body coloration, morphology, and postembryonic growth rates.
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rpl-7 | F53G12.10 | WBGene00004418 |
rpl-7 encodes a large ribosomal subunit L7 protein required in mass RNAi assays for embryonic viability and normally rapid growth.
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rps-0 | B0393.1 | WBGene00004469 |
rps-0 encodes a small ribosomal subunit SA protein that appears to function as both a ribosomal component and a laminin receptor; by homology, RPS-0 is predicted to play roles in protein biosynthesis and cell adhesion; in C. elegans, RPS-0 activity is required for embryonic and germline development, vulval morphogenesis, and the overall health of the animal.
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rps-14 | F37C12.9 | WBGene00004483 |
rps-14 encodes a small ribosomal subunit S14 protein; by homology, RPS-14 is predicted to function in protein biosynthesis; in C. elegans, RPS-14 activity is required for embryonic and germline development, as well as the overall health of the animal.
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rps-16 | T01C3.6 | WBGene00004485 |
rps-16 encodes a small ribosomal subunit S16 protein.
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rps-17 | T08B2.10 | WBGene00004486 |
rps-17 encodes a small ribosomal subunit S17 protein.
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rps-19 | T05F1.3 | WBGene00004488 |
rps-19 encodes a small ribosomal subunit S19 protein, orthologous to human RPS19 (OMIM:603474, mutated in Diamond-Blackfan anemia).
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rps-2 | C49H3.11 | WBGene00004471 |
rps-2 encodes a small ribosomal subunit S2 protein.
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rps-23 | F28D1.7 | WBGene00004492 |
rps-23 encodes a small ribosomal subunit S23 protein; by homology, RPS-23 is predicted to function in protein biosynthesis; in C. elegans, RPS-23 activity is required for germline development, vulval morphogenesis, and the overall health of the animal.
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rps-26 | F39B2.6 | WBGene00004495 |
rps-26 encodes a small ribosomal subunit S26 protein; by homology, RPS-26 is predicted to function in protein biosynthesis; in C. elegans, RPS-26 activity is required for embryonic, larval, and germline development, as well as normal locomotion and body morphology.
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rps-27 | F56E10.4 | WBGene00004496 |
rps-27 encodes a small ribosomal subunit S27 protein.
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rps-28 | Y41D4B.5 | WBGene00004497 |
rps-28 encodes a small ribosomal subunit S28 protein.
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rps-3 | C23G10.3 | WBGene00004472 |
rps-3 encodes a small ribosomal subunit S3 protein that contains a KH RNA-binding domain and by homology,is predicted to function in protein biosynthesis; in C. elegans, RPS-3 activity is required for embryonic and germline development, as well as the overall health of the animal.
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rps-4 | Y43B11AR.4 | WBGene00004473 |
rps-4 encodes a small ribosomal subunit S4 protein.
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rps-6 | Y71A12B.1 | WBGene00004475 |
rps-6 encodes a small (40S) ribosomal subunit S6 protein; loss of rps-6 activity in adult animals extends lifespan.
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rps-9 | F40F8.10 | WBGene00004478 |
rps-9 encodes a small ribosomal subunit S9 protein.
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ubl-1 | H06I04.4 | WBGene00006725 |
ubl-1 encodes a protein similar to Drosophila ubiquitin/ ribosomal protein S27a that affects body length, fertility, and larval viability.
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Y37E3.8 | Y37E3.8 | WBGene00021350 | View |