Module
- Number
- 171
- Regulatory Genes
- 3
- Module Genes
- 6
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
ztf-12 | C01B7.1 | WBGene00015274 | 365 | View | |
nhr-25 | F11C1.6 | WBGene00003623 | 329 |
nhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods.
|
View |
F57A8.1 | F57A8.1 | WBGene00010177 | 197 | View |
CLR Predictions
37 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
C34E7.4 | C34E7.4 | WBGene00007934 | View | |
lpr-3 | W04G3.8 | WBGene00012261 |
W04G3.8 encodes a novel protein, conserved amongst nematodes; large-scale RNAi experiments indicate that W04G3.8 activity is required for normal growth rates, early larval development, and coordinated locomotion.
|
View |
noah-1 | C34G6.6 | WBGene00016422 |
noah-1 encodes a PAN and ZP domain-containing protein that is related to the Drosophila extracellular matrix component NompA (no-mechanoreceptor-potential A); loss of noah-1 function via RNAi indicates that NOAH-1 activity is essential for molting; in addition, NOAH-1 appears to be required for embryonic and larval development, vulval development, coordinated locomotion, and normal body morphology.
|
View |
sym-1 | C44H4.3 | WBGene00006366 |
sym-1 encodes a protein containing 15 contiguous leucine-rich repeats (LRRs) that functionally overlaps with sym-5 and interacts with mec-8 with respect to embryonic viability and attachment of body muscle to the extracellular cuticle; expression begins at the time of embryonic elongation and SYM-1 is secreted from the apical hypodermal surface of the embryo
|
View |
wrt-10 | ZK1290.8 | WBGene00006956 |
wrt-10 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of low-complexity sequence; WRT-10 is expressed in both male and hermaphrodite intestine; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-10 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
|
View |
Y57A10A.23 | Y57A10A.23 | WBGene00013263 | View |