Transcription regulatory networks in Caenorhabditis elegans
Gene
- Public Gene Name
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vab-8
- Sequence Name
- K12F2.2
- WB ID
- WBGene00006874
- Description
-
The vab-8 gene encodes a novel protein containing an atypical kinesin-like motor domain that is required for many posteriorly-directed cell migrations, as well as axonal outgrowth and pathfinding; vab-8 encodes two protein isoforms: VAB-8S, a novel protein expressed in migrating cells, and VAB-8L, which contains a kinesin-related domain, is expressed in neurons and functions in growth cone migrations; VAB-8 interacts with UNC-51, a serine-threonine kinase also required for axon outgrowth.
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