Transcription regulatory networks in Caenorhabditis elegans
Gene
- Public Gene Name
-
unc-89
- Sequence Name
- C09D1.1
- WB ID
- WBGene00006820
- Description
-
unc-89 encodes several protein isoforms variably characterized by the presence or absence of SH3, DH, PH, immunoglobulin and myosin light chain kinase (MLCK)-like protein kinase domains; during development, unc-89 is required for proper organization of A bands in striated muscle and thus for fully normal locomotion, pharyngeal muscle contractions, and body size; unc-89 is expressed in body wall muscle, pharyngeal muscle and some cells in the tail; UNC-89 protein isoforms localize to the middle of A-bands, consistent with UNC-89 being an M line component.
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