Gene
- Public Gene Name
- tpi-1
- Sequence Name
- Y17G7B.7
- WB ID
- WBGene00006601
- Description
- tpi-1 encodes a putative triosephosphate isomerase orthologous to human TPI1 (OMIM:190450, mutated in TPI deficiency) and Drosophila WASTED AWAY; loss of tpi-1 activity via RNAi results in increased resistance to exogenous oxidants and shortening of natural adult lifespan, both presumably due to alterations in the redox state of cells.
