Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name
sod-3  
Sequence Name
C08A9.1  
WB ID
WBGene00004932  
Description
sod-3 encodes a iron/manganese superoxide dismutase, predicted to be mitochondrial, that might defend against oxidative stress and promote normal lifespan; sod-3 mRNA levels are diminished by mutation of daf-16 and chromatin immunoprecipitation (ChIP) studies demonstrate that DAF-16 can directly bind the sod-3 promoter; heterologously expressed SOD-3 in E. coli protects against methyl viologen-induced oxidative stress.  


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