Gene
- Public Gene Name
- lin-24
- Sequence Name
- B0001.1
- WB ID
- WBGene00003010
- Description
- lin-24 encodes a protein containing a domain found in bacterial toxins such as the Bacillus sphaericus Mtx3 mosquitocidal toxin; lin-24 was originally identified in screens for mutations that result in altered vulval cell lineages and morphological examination of animals carrying a gain-of-function lin-24 mutation indicates that some of the Pn.p cells that normally make up the vulva undergo inappropriate cytotoxic cell death while others adopt inappropriate cell fates; the cytotoxic cell death seen in lin-24 mutant animals is dependent upon lin-33 and a number of programmed cell death genes, including the ced-2, ced-5, and ced-12 cell corpse engulfment genes.
