Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

ifa-1  

Sequence Name

F38B2.1  

WB ID

WBGene00002050  

Description

IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum.