Transcription regulatory networks in Caenorhabditis elegans
Gene
- Public Gene Name
-
gfi-4
- Sequence Name
- F45E4.10
- WB ID
- WBGene00001584
- Description
-
gfi-4 encodes a novel protein that was identified in screens for proteins that interact with GEI-4, a coiled-coil domain protein required for embryonic viability, fertility, and vulval morphogenesis that also interacts with GEX-2, a putative Rac-binding protein, and intermediate filaments; based on its interaction with GEI-4, GFI-4 may be predicted to play a role in intermediate filament rearrangements during germline development or embryonic or vulval morphogenesis; however, as loss of gfi-4 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GFI-4 in C. elegans development and/or behavior is not yet known.
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