Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

fbp-1  

Sequence Name

K07A3.1  

WB ID

WBGene00001404  

Description

fbp-1 encodes fructose 1,6-bisphosphatase, a gluconeogenic enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate in a reaction that reverses the third enzymatic step of glycolysis; in C. elegans, loss of fbp-1 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities; FBP-1 is orthologous to human FBP1 (OMIM:229700, mutated in FBP deficiency).