Transcription regulatory networks in Caenorhabditis elegans
Gene
- Public Gene Name
-
cki-2
- Sequence Name
- T05A6.2
- WB ID
- WBGene00000517
- Description
-
cki-2 encodes a cyclin-dependent kinase (CDK) inhibitor of the CIP/KIP family, orthologous to human CDKN1C (OMIM:600856, which when mutated leads to Beckwith-Wiedemann syndrome) that may play a role in cell cycle progression during embryogenesis; CKI-2 interacts with PCN-1, a proliferating cell nuclear antigen homolog, SMO-1, a SUMO (ubiquitin related) homolog, and the RING domain-containing protein C06A5.9.
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