Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name
ZK688.9  
Sequence Name
ZK688.9  
WB ID
WBGene00022803  
Description
ZK688.9 encodes the C. elegans ortholog of TIP41, a protein first identified in Saccharomyces cerevisiae that physically interacts with and negatively regulates activity of TAP42, a protein phosphatase 2A regulatory subunit; ZK688.9(RNAi) in wild-type animals results in fertility defects in F1 hermaphrodites, who exhibit a 80-90% decrease in the total number of eggs laid, and ~80% embryonic lethality in the F2 generation.  


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