InterPro domain: IPR045049

General Information

  • Identifier IPR045049
  • Description Choline-phosphate cytidylyltransferase Pcy1-like
  • Number of genes 279
  • Gene duplication stats Loading...
  • Associated GO terms GO:0004105   GO:0006657  

Abstract

This entry represents a group of choline-phosphate cytidylyltransferases (CCTs), including PCYT1A/B (CCT-alpha/beta) from humans and Pcy1 from budding yeasts. CCT catalyses the key rate-limiting step in CDP-choline pathway for phosphatidylcholine biosynthesis [ 1 ].


1. CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis. Prog. Lipid Res. 59, 147-71

Species distribution

Gene table