InterPro domain: IPR045046
General Information
- Identifier IPR045046
- Description Vacuolar protein sorting-associated protein 9-like
- Number of genes 213
- Gene duplication stats Loading...
- Associated GO terms GO:0016192 GO:0005085
Abstract
Proteins in this entry contain the VPS9 domain that can act as guanosine nucleotide exchange factors (GEFs) against small G proteins of the Rab5 family. In budding yeasts, Vps9 is involved in vesicle-mediated vacuolar transport [ 1 ]. This entry also includes Muk1, the second Rab5 GEF in budding yeast [ 2 ].
1. Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast. J Biol Chem 288, 18162-71
Species distribution
Gene table
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