InterPro domain: IPR045046

General Information

  • Identifier IPR045046
  • Description Vacuolar protein sorting-associated protein 9-like
  • Number of genes 213
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016192   GO:0005085  

Abstract

Proteins in this entry contain the VPS9 domain that can act as guanosine nucleotide exchange factors (GEFs) against small G proteins of the Rab5 family. In budding yeasts, Vps9 is involved in vesicle-mediated vacuolar transport [ 1 ]. This entry also includes Muk1, the second Rab5 GEF in budding yeast [ 2 ].


1. Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast. J Biol Chem 288, 18162-71

Species distribution

Gene table