InterPro domain: IPR045039

This entry represents a group acetyltransferases, including NSI from Arabidopsis, SNAT1/2 from rice and Histone acetyltransferase TAP1/2 from Glycine max (Soybean). NSI is a vascular-expressed acetyltransferase that interacts with NSP, which is a nuclear shuttle protein [ 1 ]. It has been shown to regulate the nuclear export of the viral genome and potentially other non transcriptional nuclear events in plant cells [ 2 ]. SNAT1 catalyses the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin [ 3 , 4 , 5 , 6 ]. TAP1 acts as a susceptibility factor that is hijacked by Avh52 in order to promote acetylation of histones H2A and H3 during early infection by Phytophtora sojae [ 7 ].

This entry also includes predicted N-acetyltransferases from bacteria.

1. The geminivirus nuclear shuttle protein NSP inhibits the activity of AtNSI, a vascular-expressed Arabidopsis acetyltransferase regulated with the sink-to-source transition. Plant Physiol 140, 1317-30
2. A novel Arabidopsis acetyltransferase interacts with the geminivirus movement protein NSP. Plant Cell 15, 1605-18
3. Molecular cloning of rice serotonin N-acetyltransferase, the penultimate gene in plant melatonin biosynthesis. J Pineal Res 55, 7-13
4. Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT. J Pineal Res 56, 107-14
5. Cloning and characterization of the serotonin N-acetyltransferase-2 gene (SNAT2) in rice (Oryza sativa). J Pineal Res 61, 198-207
6. Overexpression of rice serotonin N-acetyltransferase 1 in transgenic rice plants confers resistance to cadmium and senescence and increases grain yield. J Pineal Res 62
7. A Phytophthora effector recruits a host cytoplasmic transacetylase into nuclear speckles to enhance plant susceptibility. Elife 7