InterPro domain: IPR045002

This entry represents a group of delta 3,5,delta 2,4-dienoyl-CoA isomerase, including ECH1 from animals and AtDCI1 from Arabidopsis. ECH1 is an auxiliary enzyme of unsaturated fatty acid beta-oxidation [ 1 , 2 ].

This entry also includes uncharacterised bacterial proteins.

1. Delta 3,5,delta 2,4-dienoyl-CoA isomerase is a multifunctional isomerase. A structural and mechanistic study. J Biol Chem 276, 13622-7
2. Molecular identification and characterization of the Arabidopsis delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase, a peroxisomal enzyme participating in the beta-oxidation cycle of unsaturated fatty acids. Plant Physiol 138, 1947-56