InterPro domain: IPR044898

General Information

  • Identifier IPR044898
  • Description Cyclin-dependent kinase inhibitor domain superfamily
  • Number of genes 610
  • Gene duplication stats Loading...

Abstract

Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase. This superfamily represents a domain found in CDIs [ 1 ].


1. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev. 9, 639-49

Species distribution

Gene table