InterPro domain: IPR044836
General Information
- Identifier IPR044836
- Description TOM1-like protein, plant
- Number of genes 1100
- Gene duplication stats Loading...
- Associated GO terms GO:0043328 GO:0043130 GO:0035091
Abstract
This entry includes TOM1-like protein 1-9 (TOL1-9) from Arabidopsis [ 1 , 2 ]. In general, they contain the VHS and GAT domains that bind to phospholipids and ubiquitin [ 3 ]. They may be part of the ESCRT (Endosomal Sorting Complex Required for Transport) complex contributing to the sorting of ubiquinated proteins to the MVB (multivesicular body) formation machinery. In plants they play a role in the control of plant morphogenesis [ 4 ]. This entry also includes TOM1 from Dictyostelium discoideum [ 4 ].
1. Arabidopsis TOL proteins act as gatekeepers for vacuolar sorting of PIN2 plasma membrane protein. Curr Biol 23, 2500-5
2. Expression of Arabidopsis TOL genes. Plant Signal Behav 9, e28667
3. Dictyostelium Tom1 participates to an ancestral ESCRT-0 complex. Traffic 10, 161-71