InterPro domain: IPR044831

This entry represents a group of heme-binding peroxidases mostly from plants and fungi, including Ccp1 from budding yeasts and APX1-6 from Arabidopsis. APX1 is a L-ascorbate peroxidase that acts as a central component of the reactive oxygen gene network of Arabidopsis [ 1 ]. Ccp1 is a mitochondrial cytochrome-c peroxidase that acts as hydrogen peroxide sensor and modulates antioxidant defense [ 2 ].

1. Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis. Plant Cell 17, 268-81
2. Cytochrome c peroxidase is a mitochondrial heme-based H2O2 sensor that modulates antioxidant defense. Free Radic Biol Med 65, 541-551