InterPro domain: IPR044801

General Information

  • Identifier IPR044801
  • Description Filamin family
  • Number of genes 128
  • Gene duplication stats Loading...
  • Associated GO terms GO:0051015   GO:0030036  

Abstract

Filamin family consists of Filamin-A (FLN-A), Filamin-B (FLN-B) and Filamin-C (FLN-C). They are a group of actin binding proteins that may be involved in actin microfilaments organisation [ 1 ].

This entry also includes gelation factor AbpC from Dictyostelium discoideum [ 2 ] and protein GAMETE EXPRESSED 2 from Arabidopsis [ 3 ].


1. The many faces of filamin: a versatile molecular scaffold for cell motility and signalling. Nat. Cell Biol. 6, 1034-8
2. Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod. Nat. Struct. Biol. 6, 836-41
3. Gamete attachment requires GEX2 for successful fertilization in Arabidopsis. Curr Biol 24, 170-175

Species distribution

Gene table