InterPro domain: IPR044764

General Information

  • Identifier IPR044764
  • Description DDX52/Rok1, DEAD-box helicase domain

Abstract

This entry represents the DEAD-box helicase domain found in DDX52 from animals and Rok1 from yeasts. This domain contains the ATP-binding region. Rok1 is an RNA helicase involved in pre-rRNA processing and in control of cell cycle progression [ 1 ]. In humans, DDX52 is ubiquitously expressed in testis, endometrium, and other tissues [ 2 ].


1. Upstream open reading frames regulate the cell cycle-dependent expression of the RNA helicase Rok1 in Saccharomyces cerevisiae. FEBS Lett 584
2. Comparative structural analysis of human DEAD-box RNA helicases. PLoS ONE 5, 4593-8

Species distribution

Gene table