InterPro domain: IPR044751

This CBS domain is found associated with CorC_HlyC domain and/or CNNM domain, domains that are related to metal ion transport. This domain consists of a CBS pair which is thought to play a regulatory role, although its exact function is not clear. This domain is found in highly conserved proteins that either have unknown function or are predicted to be hemolysins, exotoxins involved in lysis of red blood cells in vitro [ 1 ].

1. Identification and molecular analysis of the gene encoding Rickettsia typhi hemolysin. Infect Immun 67, 6104-8