InterPro domain: IPR044670

This entry represents the SUPPRESSOR OF PHYTOCHROME B (SOB) five-Like (SOFL) family of novel plant-specific proteins which have high sequence similarity and similar protein structures [ 1 , 2 ]. These proteins are involved in cytokinin-mediated development and contain two highly conserved domains SOFL-A and SOFL-B, which are necessary for their function [ 3 ]. These proteins are positive modulators of the endogenous content of specific cytokinin levels derived from the biosynthetic intermediates trans-zeatin riboside monophosphate (tZRMP) and N6-(Delta2-isopentenyl)adenosine monophosphate (iPRMP) such as N-glucosides trans-zeatin 7-glucoside (tZ7G), cis-zeatin 7-glucoside (cZ7G) and N6-(Delta2-isopentenyl)adenine 7-glucoside (iP7G) [ 3 , 3 ].

1. AtSOFL1 and AtSOFL2 act redundantly as positive modulators of the endogenous content of specific cytokinins in Arabidopsis. PLoS One 4, e8236
2. Synopsis of the SOFL Plant-Specific Gene Family. G3 (Bethesda) 8, 1281-1290