InterPro domain: IPR044625
General Information
- Identifier IPR044625
- Description Sterol methyltransferase SMT2/3-like
- Number of genes 208
- Gene duplication stats Loading...
- Associated GO terms GO:0008168 GO:0032259
Abstract
This entry represents a group of plant sterol methyltransferases, including SMT2/3 from Arabidopsis and TMT-2 from Botryococcus braunii. SMT2/3 are sterol methyltransferases that catalyse the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol [ 1 ]. They affect Arabidopsis development through nonbrassinosteroid products [ 2 ]. TMT-2 is a methyltransferase that may transfer a methyl group from AdoMet (SAM) to squalene to form mono- or dimethylated squalene [ 3 ].
1. Transformation of Saccharomyces cerevisiae with a cDNA encoding a sterol C-methyltransferase from Arabidopsis thaliana results in the synthesis of 24-ethyl sterols. FEBS Lett. 381, 87-92
2. The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products. Plant Physiol. 153, 741-56
3. Functional identification of triterpene methyltransferases from Botryococcus braunii race B. J. Biol. Chem. 287, 8163-73