InterPro domain: IPR044624

This entry represents a group of tetratricopeptide-like repeat chloroplast proteins, including MBB1/NAC2 from Chlamydomonas reinhardtii and HCF107 from Arabidopsis. MBB1 is required for expression of the chloroplast psbB/psbT/psbH gene cluster [ 1 ]. NAC2 is involved in psbD mRNA stability [ 2 ]. HCF107 is a sequence-specific RNA binding protein involved in RNA stabilizing, RNA processing, and translational activation in chloroplast [ 3 ]. It is required for processing, stabilization and translation of plastid-encoded psbH mRNA [ 4 , 5 ].

1. Characterization of Mbb1, a nucleus-encoded tetratricopeptide-like repeat protein required for expression of the chloroplast psbB/psbT/psbH gene cluster in Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. U.S.A. 97, 14813-8
2. The Nac2 gene of Chlamydomonas encodes a chloroplast TPR-like protein involved in psbD mRNA stability. EMBO J. 19, 3366-76
3. RNA binding and RNA remodeling activities of the half-a-tetratricopeptide (HAT) protein HCF107 underlie its effects on gene expression. Proc. Natl. Acad. Sci. U.S.A. 109, 5651-6
4. Expression of a nuclear-encoded psbH gene complements the plastidic RNA processing defect in the PSII mutant hcf107 in Arabidopsis thaliana. Plant J. 80, 292-304
5. The nucleus-encoded HCF107 gene of Arabidopsis provides a link between intercistronic RNA processing and the accumulation of translation-competent psbH transcripts in chloroplasts. Plant Cell 13, 2127-41