InterPro domain: IPR044604

This entry represents a group of plant FCS-Like Zinc finger proteins, including FLZ12/13/14 from Arabidopsis [ 1 ]. They are adaptor proteins which facilitate the interaction of kinase SnRK1 with other proteins [ 2 ]. The FLZ domain of FLZ12 alone has been found to be sufficient to mediate interaction with SnRK1alpha subunit [ 3 ].

1. The complex becomes more complex: protein-protein interactions of SnRK1 with DUF581 family proteins provide a framework for cell- and stimulus type-specific SnRK1 signaling in plants. J Biol Chem 5, 54
2. The FCS-like zinc finger scaffold of the kinase SnRK1 is formed by the coordinated actions of the FLZ domain and intrinsically disordered regions. null 293, 13134-13150