InterPro domain: IPR044588

General Information

  • Identifier IPR044588
  • Description PX domain-containing protein EREX-like
  • Number of genes 255
  • Gene duplication stats Loading...
  • Associated GO terms GO:0015031  

Abstract

This entry represents a group of plant PX domain-containing proteins, including EREX and EREL1/2 from Arabidopsis. EREX interacts with ARA7 and RHA1 (RAB5 members), whereas EREL1/2 was not shown to interact with these RAB5 members. EREX serves as an effector of canonical RAB5 GTPases and regulates membrane trafficking to protein storage vacuole. EREX and EREL1 act in the same trafficking and developmental events, while EREL2 has a partially redundant function with EREX and EREL1 [ 1 ].


1. ENDOSOMAL RAB EFFECTOR WITH PX-DOMAIN, an Interacting Partner of RAB5 GTPases, Regulates Membrane Trafficking to Protein Storage Vacuoles in Arabidopsis. Plant Cell 28, 1490-503

Species distribution

Gene table