InterPro domain: IPR044561

General Information

  • Identifier IPR044561
  • Description L-threonine ammonia-lyase, ACT domain
  • Number of genes 2
  • Gene duplication stats Loading...

Abstract

This entry represents the ACT domain found in L-threonine ammonia-lyase from Geobacter sulfurreducens which catalyses the conversion of threonine to 2-oxobutanoate and ammonia. It acts in the threonine-dependent pathway of isoleucine biosynthesis, which is the minor pathway for isoleucine biosynthesis in G.sulfurreducens [ 1 ].

This entry also includes the uncharacterized protein MJ1601 from Methanocaldococcus jannaschii.


1. Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens. J. Bacteriol. 190, 2266-74

Species distribution

Gene table