InterPro domain: IPR044557

This entry includes WUSCHEL-related homeobox 8/9 (WOX8/9) from Arabidopsis [ 1 ]. They are homeodomain transcription factors that required for embryo development [ 2 , 3 ]. Cytokinin signaling has been shown to be involved in activation of WOX9 expression in meristematic tissues, which is essential for maintaining the meristematic fate [ 4 ]. WOX8 promotes cotyledon boundary formation [ 5 ].

1. Large-scale phylogenomic analysis suggests three ancient superclades of the WUSCHEL-RELATED HOMEOBOX transcription factor family in plants. PLoS One 14, e0223521
2. WOX2 and STIMPY-LIKE/WOX8 promote cotyledon boundary formation in Arabidopsis. Plant J 72, 674-82
3. Combinations of WOX activities regulate tissue proliferation during Arabidopsis embryonic development. Dev Biol 309, 306-16
4. STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings. Development 137, 541-9