InterPro domain: IPR044300

This entry represents a group of plant zinc finger proteins, including STOP1/STOP2 from Arabidopsis and their homologues, Os01g0871200/STAR3 from rice. They are putative transcription factors that regulate gene expression associated with multiple stress tolerances in plant roots [ 1 , 2 , 3 ]. STOP1 (sensitive to proton rhizotoxicity 1) regulates transcription of multiple genes critical for tolerance to aluminum (Al) and low pH in Arabidopsis [ 4 ]. STOP2 is a physiologically minor isoform of STOP1, but it can activate expression of some genes regulated by STOP1 [ 5 ]. In rice, ART1 regulates multiple genes implicated in aluminum tolerance [ 6 ].

1. STOP1 regulates the expression of HsfA2 and GDHs that are critical for low-oxygen tolerance in Arabidopsis. J Exp Bot 70, 3297-3311
2. Characterization of AtSTOP1 orthologous genes in tobacco and other plant species. Plant Physiol 162, 1937-46
3. The roles of STOP1-like transcription factors in aluminum and proton tolerance. Plant Signal Behav 11, e1131371
4. Zinc finger protein STOP1 is critical for proton tolerance in Arabidopsis and coregulates a key gene in aluminum tolerance. Proc Natl Acad Sci U S A 104, 9900-5
5. STOP2 activates transcription of several genes for Al- and low pH-tolerance that are regulated by STOP1 in Arabidopsis. Mol Plant 7, 311-22
6. A zinc finger transcription factor ART1 regulates multiple genes implicated in aluminum tolerance in rice. Plant Cell 21, 3339-49