InterPro domain: IPR044297

This entry represents a group of plant cellulose synthase interacting proteins, including CSI1/2/3 from Arabidopsis. They are non-cellulose synthase (CESA) proteins associated with cellulose synthase complexes [ 1 ] and are required for cellulose biosynthesis [ 2 ]. CSI1 is also a microtubule-associated protein that bridges CESA complexes and cortical microtubules [ 3 ]. CSI3 has been shown to regulate plant cellulose biosynthesis and plant anisotropic cell growth that modulates the velocity of cellulose synthase complexes in both a microtubule-dependent and microtubule-independent manner [ 4 ].

1. Cellulose synthase interacting protein: a new factor in cellulose synthesis. Plant Signal Behav 5, 1571-4
2. Identification of a cellulose synthase-associated protein required for cellulose biosynthesis. Proc Natl Acad Sci U S A 107, 12866-71
3. Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc Natl Acad Sci U S A 109, 185-90
4. Cellulose synthase INTERACTIVE3 regulates cellulose biosynthesis in both a microtubule-dependent and microtubule-independent manner in Arabidopsis. Plant Cell 25, 4912-23