InterPro domain: IPR044293
General Information
- Identifier IPR044293
- Description Transcription factor PRE
- Number of genes 523
- Gene duplication stats Loading...
- Associated GO terms GO:0006355 GO:0046983 GO:0040008
Abstract
This entry represents the paclobutrazol-resistant (PRE) family of helix-loop-helix (HLH) factors, including PRE1-6 from Arabidopsis. They are involved in development in Arabidopsis and rice [ 1 , 2 ]. They lack the basic domain required for DNA binding but dimerizes with DNA binding bHLH factors to inhibit their DNA binding. Moreover, they also antagonize their interacting HLH or bHLH proteins [ 3 ].
1. Overexpression of PRE1 and its homologous genes activates Gibberellin-dependent responses in Arabidopsis thaliana. Plant Cell Physiol 47, 591-600
2. Antagonistic HLH/bHLH transcription factors mediate brassinosteroid regulation of cell elongation and plant development in rice and Arabidopsis. Plant Cell 21, 3767-80
3. A triple helix-loop-helix/basic helix-loop-helix cascade controls cell elongation downstream of multiple hormonal and environmental signaling pathways in Arabidopsis. Plant Cell 24, 4917-29