InterPro domain: IPR044284

This entry represents a group of plant BTB/POZ domain and ankyrin repeat-containing proteins, including NPR5/6 from Arabidopsis and NOOT1 from Medicago truncatula [ 1 , 2 ].

NPR5 and NPR6, also known as BLADE ON PETIOLE 2 and 1 (BOP2/1), regulates Arabidopsis thaliana lateral organ cell fate and polarity through regulation of LOB domain and adaxial-abaxial polarity genes [ 3 ]. They function as transcriptional activators during Arabidopsis thaliana leaf formation [ 4 , 5 ]. They are also required for maintaining floral fate [ 6 ].

In Gossypium hirsutum BLADE-ON-PETIOLE1 homologue, GhBOP1, is involved in in plant defence against a fungal pathogen [ 7 ].

1. NODULE ROOT and COCHLEATA maintain nodule development and are legume orthologs of Arabidopsis BLADE-ON-PETIOLE genes. Plant Cell 24, 4498-510
2. MtNODULE ROOT1 and MtNODULE ROOT2 Are Essential for Indeterminate Nodule Identity. Plant Physiol 178, 295-316
3. BLADE-ON-PETIOLE 1 and 2 control Arabidopsis lateral organ fate through regulation of LOB domain and adaxial-abaxial polarity genes. Plant Cell 19, 1809-25
4. BLADE-ON-PETIOLE1 coordinates organ determinacy and axial polarity in arabidopsis by directly activating ASYMMETRIC LEAVES2. Plant Cell 22, 62-76
5. Control of Arabidopsis leaf morphogenesis through regulation of the YABBY and KNOX families of transcription factors. Genetics 186, 197-206
6. Arabidopsis BLADE-ON-PETIOLE1 and 2 promote floral meristem fate and determinacy in a previously undefined pathway targeting APETALA1 and AGAMOUS-LIKE24. Plant J 63, 974-89
7. Cotton plant defence against a fungal pathogen is enhanced by expanding BLADE-ON-PETIOLE1 expression beyond lateral-organ boundaries. Commun Biol 2, 238