InterPro domain: IPR044250

General Information

  • Identifier IPR044250
  • Description Isochorismate synthase MenF-like
  • Number of genes 209
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008909  

Abstract

This entry represents a group of Isochorismate synthases, including MenF from bacteria and AtIcs1/2 from Arabidopsis. MenF catalyses the conversion of chorismate to isochorismate, the initial step of menaquinone biosynthesis [ 1 ]. ICS1 and ICS2 are targeted to the plastids and are involved in the salicylic acid (SA) biosynthesis [ 2 ].


1. Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family. Biochemistry 46, 946-53
2. Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis. Plant Physiol 147, 1279-87

Species distribution

Gene table

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