InterPro domain: IPR044204
General Information
- Identifier IPR044204
- Description Protein IWS1 homolog 1/2
- Number of genes 222
- Gene duplication stats Loading...
- Associated GO terms GO:0032784 GO:0009742
Abstract
This entry represents a group of IWS1 plant homologues, including AtIWS1/2 from Arabidopsis. AtIWS1, also known as HNI9, is an evolutionary conserved component of the RNA polymerase II complex. It plays a role in N signaling by regulating several hundred N-responsive genes in roots [ 1 ]. It interacts with transcription factor BES1 and is involved in plant steroid hormone brassinosteroid regulated gene expression [ 2 ].
1. High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation. Proc Natl Acad Sci U S A 108, 13329-34
2. Arabidopsis IWS1 interacts with transcription factor BES1 and is involved in plant steroid hormone brassinosteroid regulated gene expression. Proc Natl Acad Sci U S A 107, 3918-23