InterPro domain: IPR044165
General Information
- Identifier IPR044165
- Description Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4, plant
- Number of genes 115
- Gene duplication stats Loading...
Abstract
This entry represents OST4 from plants, including OST4A/4B/4C from Arabidopsis. They share the protein sequence similarity with animals OST4, which is part of the oligosaccharyl transferase (OST) complex that catalyses the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation [ 1 ].
1. OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation. J. Cell. Sci. 126, 2595-606
Species distribution
Gene table
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