InterPro domain: IPR044122

This entry represents the uncharacterised UPF0261 domain. It is present at the N terminus of the tomato resistance protein Tm-1, which inhibits replication complex formation through its binding to tomato mosaic virus (ToMV) replication proteins. It contains an ATP-binding site required for interaction with ToMV proteins [ 1 , 2 ].

1. Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1. Proc. Natl. Acad. Sci. U.S.A. 111, E3486-95
2. Origin of the plant Tm-1-like gene via two independent horizontal transfer events and one gene fusion event. Sci Rep 6, 33691