InterPro domain: IPR043323

General Information

  • Identifier IPR043323
  • Description Peptidyl-prolyl cis-trans isomerase PIN4

Abstract

PIN4, also known as Par14, is a member of the parvulin family of peptidyl-prolyl cis-trans isomerases. It is involved in rRNA processing, microtubule formation and the glucose metabolism [ 1 ]. It also binds DNA and associates with chromatin [ 2 ].


1. Parvulin (Par14), a peptidyl-prolyl cis-trans isomerase, is a novel rRNA processing factor that evolved in the metazoan lineage. Mol. Cell Proteomics 8, 1552-65
2. Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivo. BMC Biochem. 16, 4

Species distribution

Gene table