InterPro domain: IPR043130

General Information

  • Identifier IPR043130
  • Description CDP-alcohol phosphotransferase, transmembrane domain
  • Number of genes 685
  • Gene duplication stats Loading...

Abstract

The CDP-alcohol phosphotransferase (CDP-AP) family of integral membrane enzymes catalyses the transfer of a substituted phosphate group from a CDP-linked donor to an alcohol acceptor. This is an essential reaction for phospholipid biosynthesis across all kingdoms of life, and it is catalysed solely by CDP-APs [ 1 ]. This entry represents the transmembrane (TM) domain of CDP-alcohol phosphotransferase which is made up of 7 alpha helices.


1. Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun 5, 4068

Species distribution

Gene table