InterPro domain: IPR043009

General Information

  • Identifier IPR043009
  • Description LOR/SDH bifunctional enzyme, conserved domain superfamily
  • Number of genes 110
  • Gene duplication stats Loading...

Abstract

Lysine-oxoglutarate reductase/Saccharopine dehydrogenase (LOR/SDH) is a bifunctional enzyme. LOR is also known as LKR (lysine-ketoglutarate reductase), and thus LOR/SDH is sometimes termed LKR/SDH. This superfamily represents the conserved region, commonly found immediately N-terminal to saccharopine dehydrogenase conserved region in eukaryotes [ 1 , 2 ].


1. Lysine-ketoglutarate reductase and saccharopine dehydrogenase from Arabidopsis thaliana: nucleotide sequence and characterization. Plant Mol. Biol. 35, 735-48
2. Structure and regulation of the bifunctional enzyme lysine-oxoglutarate reductase-saccharopine dehydrogenase in maize. Eur. J. Biochem. 253, 720-9

Species distribution

Gene table