InterPro domain: IPR042561

The exocyst is a large complex that is required for tethering vesicles at the final stages of the exocytic pathway in all eukaryotes. Exocyst subunits are composed of mostly helical modules strung together into long rods [ 1 ].

This superfamily represents the subdomain 1 found in the C-terminal helical region of the exocyst component Exo84. The C-terminal region resembles a cullin-repeat, a multi-helical bundle.

1. The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif. Nat. Struct. Mol. Biol. 12, 1094-100